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CCR2-RA-[R]

Chemical Structure : CCR2-RA-[R]

CAS No.: 512177-83-2

CCR2-RA-[R] (CCR2-RA [R])

Catalog No.: PC-60323Not For Human Use, Lab Use Only.

CCR2-RA-[R] is a potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CCR2-RA-[R] is a potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM.

Physicochemical Properties

M.Wt 351.802
Formula C18H19ClFNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one

References

1. Zheng Y, et al. Nature. 2016 Dec 15;540(7633):458-461.

2. Zweemer AJ, et al. Mol Pharmacol. 2013 Oct;84(4):551-61.

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